Welcome to the Homepage of the DFG Research Unit FOR2509
The Concert of Dolichol-Based Glycosylation:
From Molecules to Disease Models
The research consortium FOR 2509 is funded by the German research foundation (DFG). It joins experts in N-glycosylation, C- and O-mannosylation, in structural and lipid biochemistry, in proteomics, glycoproteomics, glycomics and lipidomics, as well as in developmental biology which aim to understand the molecular pathology of dolichol-based glycosylation disorders. You will find here all relevant information about the group leaders, their projects and the activities of the group.
July 27th, 2021 Annual Meeting 2021 goes virtual
31st Joint Glycobiology Meeting 2021 ONLINE | October 7–8, 2021
– A new ALG3 medaka fish model has been created by the group of Jochen Wittbrodt and Thomas Thumberger in collaboration with the groups of Christian Thiel, Erdmann Rapp and Thomas Ruppert. The paper entitled „A patient-based medaka alg2 mutant as a model for hypo-N-glycosylation“ published in DEVELOPMENT is now online. We congratulate Sevinc Gücüm and coworkers for their exciting work! Please check out the press release and the cover page image.
– We congratulate Karsten Cirksena for his new insights into the function of C-mannosylation. The paper entitled „The C-mannosylome of human induced pluripotent stem cells implies a role for ADAMTS16 C-mannosylation in eye development“ published in Molecular & Cellular Proteomics is now online. A great collaboration between the groups of Falk Büttner, Hans Bakker, Jochen Wittbrodt and Thomas Ruppert!